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Fig. 1 | Nanoscale Research Letters

Fig. 1

From: Restored microRNA-326-5p Inhibits Neuronal Apoptosis and Attenuates Mitochondrial Damage via Suppressing STAT3 in Cerebral Ischemia/Reperfusion Injury

Fig. 1

Up-regulation of miR-326-5p or down-regulation of STAT3 attenuates apoptosis of OGD-treated cortical neurons. a Cerebral neurons with 2-d adherent culture (scale bar: 100 μm); b Cerebral neurons with 7-d adherent culture (scale bar: 100 μm); c Cerebral neurons with 7-d adherent culture stained by NES immunofluorescence assay (scale bar: 50 μm); d Viability of OGD-treated cortical neurons by MTT assay; e Apoptosis of OGD-treated cortical neurons detected by flow cytometry; f Apoptosis rate of OGD-treated cortical neurons; g Bcl-2 and Bax mRNA expression in OGD-treated cortical neurons; *P < 0.05 compared with the control group; #P < 0.05 compared with the NC group; &P < 0.05 compared with the miR-326-5p agomir group

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