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Fig. 2 | Nanoscale Research Letters

Fig. 2

From: Restored microRNA-326-5p Inhibits Neuronal Apoptosis and Attenuates Mitochondrial Damage via Suppressing STAT3 in Cerebral Ischemia/Reperfusion Injury

Fig. 2

Up-regulation of miR-326-5p or down-regulation of STAT3 increases Mfn2 and mitochondrial membrane potential level in OGD-treated cortical neurons. a, b Mfn2 protein expression in OGD-treated cortical neurons; c JC-1 flow cytometry of mitochondrial membrane potential level in OGD-treated cortical neurons; d ROS content in OGD-treated cortical neurons after up-regulating miR-326-5p or down-regulating STAT3; e GSH activity in OGD-treated cortical neurons after up-regulating miR-326-5p or down-regulating STAT3; f MDA content in OGD-treated cortical neurons after up-regulating miR-326-5p or down-regulating STAT3; g SOD activity in neurons after up-regulating miR-326-5p or down-regulating STAT3; *P < 0.05 compared with the control group; #P < 0.05 compared with the NC group; &P < 0.05 compared with the miR-326-5p agomir group

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