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Fig. 4 | Nanoscale Research Letters

Fig. 4

From: Restored microRNA-326-5p Inhibits Neuronal Apoptosis and Attenuates Mitochondrial Damage via Suppressing STAT3 in Cerebral Ischemia/Reperfusion Injury

Fig. 4

Up-regulation of miR-326-5p or down-regulation of STAT3 increases mitochondrial membrane potential level in brain tissues in rats with CI/RI. a Mfn2 expression detected by immunohistochemistry in rat brain tissue (scale bar: 50 μm); b Number of Mfn2-positive cells in MCAO rat brain tissues after up-regulating miR-326-5p or down-regulating STAT3; c Mitochondrial transmembrane potentials in neurons of MCAO rat brain tissues after up-regulating miR-326-5p or down-regulating STAT3; *P < 0.05 compared with the sham group; #P < 0.05 compared with the NC group; &P < 0.05 compared with the miR-326-5p agomir group

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