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Table 1 Comparison among currently available sensing systems for interleukins

From: Longitudinal Zeolite-Iron Oxide Nanocomposite Deposited Capacitance Biosensor for Interleukin-3 in Sepsis Detection

Biosensor Target Probe Detection limit References
Optic biosensor IL-6 5 pM [38]
Plasmonic sensor IL-6 Antibody 0.1 pg/mL [20]
ELISA IL-10 Antibody 1–15 pg/mL [39]
Impedance biosensor IL-8 Synthetic binding protein 90 fg/mL [40]
Field effect transistor IL-6 1.53 pg/mL [21]
Chemiluminescent biosensor IL-5 Antibody 0.1 pg/mL [41]
Fluorescence assay IL-6 Antibody 11.859 pg/mL [42]
Electrochemical sensor IL-8 Stem loop probe 200 pM [22]
Wearable nonfaradaic sensor IL-6 Antibody 0.2 pg/mL [43]
Impedance spectroscopy IL-3 Antibody 3 pg/mL This work