Fig. 5

Restored miR-499-5p or depleted Sox6 raises SOD, CAT and GSH-Px activities as well as reduces MDA and MPO contents in lung tissues of sepsis-induced lung injury mice. a SOD activity in lung tissues of mice. b MDA content in lung tissue of mice. c GSH-Px activity in lung tissues of mice. d CAT activity in lung tissues of each group of mice. e MPO content in lung tissues of mice. (a) P < 0.05 versus the sham group. (b) P < 0.05 versus the agomir NC group. (c) P < 0.05 versus the si-NC group. (d) P < 0.05 versus the miR-499-5p agomir + oe-NC group. Measurement data were depicted as mean ± standard deviation, and data were assessed by one-way ANOVA followed by Tukey’s post hoc test