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Fig. 4 | Nanoscale Research Letters

Fig. 4

From: CoFe2O4-Quantum Dots for Synergistic Photothermal/Photodynamic Therapy of Non-small-Cell Lung Cancer Via Triggering Apoptosis by Regulating PI3K/AKT Pathway

Fig. 4

In vitro combination of CoFe2O4-QDs and NIR induces NSCLC apoptosis. a, b H460 and A549 NSCLCs were treated with the combination of CoFe2O4-QDs and NIR laser for 5 min. The apoptotic cells were evaluated by Annexin-V staining and detected by FACS. Quantification is shown respectively as well. The data were shown as mean ± SD, N = 3. **P < 0.01 vs Control, NIR, CoFe2O4 groups. c, d The protein level of Bcl-2 and Bax were determined by Western blot analysis in NCI-H460 and A549 NSCLC after treatment. Representative images are shown. The quantification is shown after calibrating to the expression of internal control β-Actin. The data were shown as mean ± SD, N = 3. *P < 0.05 vs Control, NIR, CoFe2O4 groups

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