Fig. 9
From: Brain-Targeted Polysorbate 80-Emulsified Donepezil Drug-Loaded Nanoparticles for Neuroprotection
Effect of DZP-CHP on Aβ25-35-injured PC12 and SH-SY5Y cells. a and b The effects of DZP-CHP on the cell survival rate, LDH activity, and mitochondrial membrane potential of PC12 and SH-SY5Y cells injured by Aβ25-35 (#P < 0.05, ## P < 0.01 vs Aβ25-35 group; ▲ P < 0.05 vs DZP group). c The effect of DZP-CHP on the apoptosis morphology of PC12 cells injured by Aβ25-35; a—control group, b—Aβ25-35 injury group, c—DZP (5 µM), d—DZP -CHP (5 µM), e—DZP (10 µM), f—DZP-CHP (10 µM). D: the effect of DZP-CHP on the apoptosis morphology of SH-SY5Y cells injured by Aβ25-35; g—control group, h—Aβ25-35 injury group, i—DZP (5 µM), j—DZP-CHP (5 µM), k—DZP (10 µM), l—DZP-CHP (10 µM). E: red/green fluorescence ratio