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Table 2 Validation of the LSPR-based method by comparing its performance with conventional tests

From: Gold Nanobiosensor Based on the Localized Surface Plasmon Resonance is Able to Diagnose Human Brucellosis, Introducing a Rapid and Affordable Method

Methods	Positive	Negative	Sen (%)	Spc (%)	NPV (%)	PPV (%)
A. Gold Standard	20	20	–	–	–	–
B. SAT
Positive	18	1	90	95	90	94
Negative	2	19	90	95	90	94
C. IgG
Positive	17	1	85	95	90	89
Negative	3	19	85	95	90	89
D. IgM
Positive	16	2	80	90	91	88
Negative	4	18	80	90	91	88
E. LSPR
Positive	17	0	85	100	86	100
Negative	3	20	85	100	86	100

The obtained results emphasize the appropriate and comparable performance of the designed method
Sen, Sensitivity; Spc, Specificity; NPV, Negative Predictive Value; PPV, Positive Predictive Value

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