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Table 1 Antimicrobial activities of AuNP loaded with some of the FDA-approved drugs

From: Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review

Drug Drug type Core sizes (nm) Shape Test microorganisms Ref
Ciprofloxacin Antibiotic 15 Gold silica nanoshells E. coli DH5α
Lactococcus lactis
[152]
Cefaclor Antibiotic 23–52 Spheres S. aureus
E. coli
[149]
Lincomycin Antibiotic    S. aureus
S. pyogenes
[4]
Vancomycin Antibiotic    Vancomycin-resistant strains (VRE) [150]
Ampicilin Antibiotic 1.43 Spheres assembled into rosette nanotube S. aureus
MRSA
[151]
Rifampicin Antibiotic 28 Spheres N/T [153]
Kanamycin Antibiotic 20 Spheres Streptococcus bovis (S. bovis)
Staphylococcus epidermidis (S. epidermidis)
Enterobacter aerogenes (E. aerogenes)
Pseudomonas aeruginosa
(P. aeruginosa)
Yersinia pestis (Y. pestis)
[21]
4,6-diamino-2-pyrimidinethiol (DAPT) Inactive alone 5 / 16.57 Spheres S. aureus
E. coli
P. aeruginosa
E. coli infected mice
[13, 112]
5FU Anti-leukemic drug 18 Spheres Micrococcus luteus
S. aureus
P. aeruginosa
E. coli
Aspergillus fumigatus
Aspergillus niger
[58]
Metformin Anti-hyperglycemic drug 3.1   S. aureus
E. coli
P. aeruginosa
[13]
  1. N/T not tested