Fig. 5

Suppression of miR-216b antagonizes silenced LINC01354-induced impacts on EC cell development. a KRAS expression was lowered in lshikawa cells after silencing both LINC01354 and miR-216b (RT-qPCR and Western blot); b Cell viability was enhanced after silencing both LINC01354 and miR-216b (MTT assay); c Cell apoptosis rate was reduced after silencing both LINC01354 and miR-216b (flow cytometry); d Cell migration was accelerated after silencing both LINC01354 and miR-216b (scratch test); e Cell invasion was augmented after silencing both LINC01354 and miR-216b (Transwell assay). The data were expressed as mean ± standard deviation (N = 3). *P < 0.05 versus the sh-LINC01354 + inhibitor NC group