Table 1 Summary of the biomolecules employed and highest resolution achieved so far with the different nanolithographic techniques
Dip-pen nanolithography | Nanoshaving | Nanografting | Electron-beam lithography | Nanocontact printing | |||
---|---|---|---|---|---|---|---|
Patterned biomolecules | Indirect | Direct | Indirect | Direct | |||
DNA | DNA | Peptides | Proteins | DNA | DNA | Proteins | |
Peptides | Peptides | Proteins | Proteins | Peptides | |||
Proteins | Proteins | Proteins | |||||
Virus | |||||||
Highest resolution | ∼85 nm | 30 nm | 150 nm | 10 nm | 10 nm | 30 nm | 70 nm |
IgG protein dot features [73] | Collagen-like peptide lines [46] | IgG protein lines [98] | Lysozyme protein lines [103] | DNA lines [106] | Collagen protein lines [123] | Titin multimer protein lines [136] |