Table 2 Characterization of micelles prepared from a series of mPEG-PLA copolymers
Copolymers | Drug-free | Drug-loaded | CACc(10−7 mol/L) | LCd(%) | EEe(%) | ||
---|---|---|---|---|---|---|---|
d a(nm) | PIb | d(nm) | PI | ||||
mPEG5-PLA2.5 | 44.33 | 0.137 | 51.57 | 0.122 | 2.31 | 16.43 | 24.22 |
mPEG5-PLA5 | 61.80 | 0.164 | 68.41 | 0.154 | 1.87 | 14.21 | 20.29 |
mPEG5-PLA10 | 79.36 | 0.127 | 84.25 | 0.106 | 1.45 | 15.52 | 19.89 |
mPEG5-PLA15 | 84.55 | 0.091 | 97.54 | 0.118 | 0.96 | 14.67 | 20.32 |