A Novel Docetaxel-Loaded Poly (ε-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment

Table 1 Characterization of nanoparticles

Group	Size (nm)(n = 3)	Polydispersion (n = 3)	Drug loading (%)	Encapsulation efficiency (%)	Zeta potential (mV)(n = 3)	Polymer
PCNP	293.2 ± 3.6	0.172	9.76	65.08	−48.70 ± 3.11	PCL
PFNP	201.7 ± 10.1	0.096	10.02	69.10	−12.50 ± 0.86	PCL/F68
CCNP	281.2 ± 5.5	0.145			−35.70 ± 2.99	PCL
CFNP	222.7 ± 5.4	0.133			−20.50 ± 1.34	PCL/F68

Note: Group CCNP and CFNP represent coumarin-6-loaded PCL nanoparticles and PCL/Pluronic F68 nanoparticles, respectively