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Table 2 Characterization of mPEG5–PLAy copolymers and polymeric micelles

From: Preparation and Evaluation of Poly(Ethylene Glycol)–Poly(Lactide) Micelles as Nanocarriers for Oral Delivery of Cyclosporine A

Copolymers

Mn(PLA)

CAC (10−7 mol/L)

CyA loaded

LC (%)

EE (%)

d(nm)

PDI

mPEG5–PLA2.5

2249

3.07

60.1 ± 8.2

0.23

12.1 ± 0.8

44.0 ± 3.0

mPEG5–PLA5

4802

1.99

71.9 ± 0.4

0.19

15.2 ± 1.1

77.9 ± 4.1

mPEG5–PLA10

9247

1.57

89.0 ± 0.5

0.20

10.7 ± 1.5

33.1 ± 2.1

mPEG5–PLA15

15825

1.08

95.2 ± 1.2

0.23

9.7 ± 0.2

10.9 ± 0.2

  1. d and PDI represent the average diameter and the polydispersity index (PDI) of micelles in aqueous solution, respectively

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