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Table 2 Effects of DMAB modification on size, entrapment efficiency and zeta potential

From: Oral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy

Group

Polymer

Size (nm)

PDI

Zeta Potential (mV)

Drug loading (%)

EE (%)

DMAB Modification (%)

ANP

PLGA

239.82 ± 8.64

0.299

-28.58 ± 4.44

8.93

88.26

5

BNP

PLGA-TPGS

253.51 ± 5.38

0.264

-21.87 ± 2.11

9.83

98.27

None

CNP

PLGA-TPGS

226.33 ± 3.56

0.251

32.23 ± 3.55

9.62

96.23

5

DNP

PLGA-TPGS

219.42 ± 5.24

0.199

34.15 ± 4.28

9.21

92.12

20

  1. PDI polydispersity index, EE drug entrapment efficiency, n = 3

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