Table 2 Applications of QDs in labeling neurons and glia cells
From: Quantum dots: synthesis, bioapplications, and toxicity
Authors | Type of QD used | Application of QD |
|---|---|---|
Dahan et al. [61] | QD-GlyR | Target neurons to investigate a specific neurophysiological process(QDs to track individual glycine receptors and analyze their lateral dynamics in the neuronal membrane) |
Pathak et al. [106] | Antibody-conjugated quantum dots | Performed the specific labeling of neurons and glia cells |
Vu et al. [110] | Tagged nerve growth factor (βNGF) to QDs | Investigate the QD nanostructure's potential to assess the neurite outgrowth |
Sundara Rajan et al. [111] | QD-anti-TrkA-TrkA receptor with transport by GFP | Immobilized QDs were conjugated with NGF, activate Trk receptors, and initiate neuronal differentiation in PC12 cells. |
Howarth et al. [112] | Tagged cell surface proteins with a specific peptide (acceptor protein) that can be directly biotinylated as a target for streptavidin-conjugated quantum dots | Specifically label and track AMPA receptors on cultured hippocampal neurons |
Prasad et al. [113] | Thioglycolic acid (TGA)-stabilized CdTe QDs | Performed imaging of PC12 cells |