Preparation and characterization of nanosized P(NIPAM-MBA) hydrogel particles and adsorption of bovine serum albumin on their surface

Table 2 Precipitation polymerization of NIPAM-MBA with varied APS levels

APS (wt%)	D₁^a(nm)	D₂^a(nm)	PDI (40°C)	Particle yield (%)	Soluble polymer (%)	Monomer conversion (%)
0.5	860	632	0.112	79.17	4.79	83.96
1.0	873	665	0.140	84.52	5.70	90.22
1.5	989	699	0.201	87.93	7.07	95.00
2.0	1,040	716	0.198	91.78	7.06	98.84
2.5^b	5,156	1,583	0.379	91.18	7.55	98.73
3.0^b	3,965	1,723	0.399	91.24	7.59	98.83

^aD₁ and D₂ are the sizes of the particles determined by light scattering at 25°C and 40°C, respectively. ^bIn these two runs, particles were observed with part of the polymer coagula. Only particles were obtained in the rest of the runs, without coagula.