Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

Table 1 Identification of candidate proteins as biomarkers

Spot	Protein name	Accession number	MW (kD)	pI	Expression ratio (nSP70/saline) (fold)
1	Haptoglobin	[Swiss-Prot:Q61646]	38.75	5.88	375.44
2	Hemopexin	[Swiss-Prot:Q91X72]	51.34	7.92	3.25
3	Alpha-1-acid glycoprotein 1	[Swiss-Prot:Q60590]	23.89	5.58	3.05
4	Inter-alpha-trypsin inhibitor	[Swiss-Prot:Q61703]	105.93	6.82	0.40
5	Complement C4-B	[Swiss-Prot:P01029]	192.89	7.38	0.39
6	Cullin-4A	[Swiss-Prot:Q3TCH7]	87.75	8.53	0.37
7	Serotransferrin	[Swiss-Prot:Q921l1]	76.72	6.94	0.30

The differentially expressed spots were identified by LC/TOF/MS. pI, isoelectric point.