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Figure 8 | Nanoscale Research Letters

Figure 8

From: The effect of two novel amino acid-coated magnetic nanoparticles on survival in vascular endothelial cells, bone marrow stromal cells, and macrophages

Figure 8

Effects of MNPs@Lys on macrophages. (A) Effects of the nanoparticles at different concentrations on cell morphology of THP-1-derived macrophages treated for 24 and 48 h. (B) Cell apoptosis or necrosis was determined by AO and EB double staining assay. (C) Cell viability was determined by WST-8 assay; the cells were treated with the nanoparticles for 48 h (**P < 0.01, ***P < 0.001 vs normal, n = 3). (D) Cell necrosis was determined by detecting the release of LDH from THP-1-derived macrophages (the cell density was 40,000/cm2, n = 3).

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