Figure 2
From: AHAPS-functionalized silica nanoparticles do not modulate allergic contact dermatitis in mice
Effects of AHAPS-SiO 2 -NP treatments on barrier function and erythema. Transepidermal water loss (TEWL) increased in oxazolone (Ox)-treated mice without significant differences between the AHAPS-SiO2-NP-treated versus ultra-pure water-treated groups. Solvent-only-treated mice failed to develop elevated TEWL values above the physiological threshold (A). Erythema was absent from the skin of the acetone solvent group (B) but present to similar degrees in the vehicle control group (C) and AHAPS-SiO2-NP-treated group (D). Data are presented as mean ± SEM; Ox-treated groups: n = 5; solvent-treated group: n = 3.