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Table 2 Top molecular functions changed after SWCNT treatment in transformed BEAS-2B cells

From: Gene expression profile of human lung epithelial cells chronically exposed to single-walled carbon nanotubes

Molecular function

Enrichment score

Enrichment p value

Percent of genes in group that are present

GO ID

MHC class I receptor activity

13.6

0.000

35.7

32393

Flavonol 3-sulfotransferase activity

7.3

0.001

66.7

47894

Aryl sulfotransferase activity

6.1

0.002

40.0

4062

G-protein coupled photoreceptor activity

6.1

0.002

40.0

8020

SH3 domain binding

6.1

0.002

5.8

17124

Ubiquitin-specific protease activity

5.7

0.003

9.8

4843

Photoreceptor activity

4.9

0.008

22.2

9881

Protein binding

4.7

0.009

1.9

5515

Ubiquitin thiolesterase activity

4.7

0.009

5.8

4221

Cysteine-type endopeptidase activity

4.5

0.011

6.9

4197

  1. The molecular function was based on SWCNT vs. control comparison, p < 0.05 and fold changes >2.

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