Table 4 The ratio of survived mice and CFU in different organs of infected mice
Log CFU gram tissue (n = 3) | Survival ratioa (%, n = 20) | ||||
---|---|---|---|---|---|
Lung | Spleen | Kidney | Liver | ||
Control (untreated) | 4.35 ± 0.27 | 3.08 ± 0.25 | 4.78 ± 0.33 | 3.41 ± 0.34 | 0.0 |
PBS | 4.29 ± 0.35 | 3.14 ± 0.21 | 4.75 ± 0.29 | 3.34 ± 0.33 | 0.0 |
Free AMB | 2.51 ± 0.11* | 1.12 ± 0.09* | 1.21 ± 0.26* | 1.87 ± 0.25* | 55.0 |
CDA-AMB-NPs | 1.01 ± 0.06*# | Nil** | Nil** | Nil** | 95.0 |