Fig. 3

Fluorescence intensities (a) and fluorescence emission scan (b) of DOX-incorporated HAssLG nanoparticles according to the GSH concentration. DOX-incorporated nanoparticles were incubated 4 h at 37 °C in the presence of GSH. Fluorescence emission spectra were recorded in the range of 520~700 nm (excitation wavelength, 486 nm). Nanoparticle concentration was 1 mg/ml (DOX contents, 7.8 % (w/w)). c DOX release from HAssLG nanoparticles in the presence (GSH(+), 10 mM) or absence (GSH(−), 0 mM) of GSH