Fig. 6

Visualization of the biodistribution of graphene oxide nanoparticles after multiple intraperitoneal injections into rats by digital camera. Solid aggregates were found in injected body regions (a, b, c) and mesentery (d). Average-sized dots of graphene oxide nanoparticle aggregates were also localized in abdominal lipid tissue (e). Black arrows indicate graphene oxide nanoparticle aggregates. The macroscopic structure of the kidney (f), lungs (g), heart (h), spleen (i), and liver (j) were also examined. There were no macroscopic pathological features on the organs