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Table 4 Mean hematologic parameters of the whole blood of rats

From: Biodistribution of a High Dose of Diamond, Graphite, and Graphene Oxide Nanoparticles After Multiple Intraperitoneal Injections in Rats

Parameters DN GN GO Placebo ANOVA
P value
White blood cells (109/L) 3.01 ± 1.748 3.08 ± 1.715 2.03 ± 1.179 3.13 ± 1.496 0.586
Lymphocytes (109/L) 2.65 ± 1.592 2.56 ± 1.473 1.75 ± 1.059 2.32 ± 0.665 0.622
Monocytes (109/L) 0.08 ± 0.059 0.10 ± 0.049 0.06 ± 0.043 0.09 ± 0.033 0.309
Granulocytes (109/L) 0.29 ± 0.207 0.43 ± 0.259 0.22 ± 0.104 0.73 ± 1.146 0.515
Red blood cells (1012/L) 6.67 ± 0.729 6.23 ± 0.674 5.88 ± 1.018 6.43 ± 0.813 0.440
Hemoglobin (g/dL) 11.8 ± 1.10 11.0 ± 1.29 10.7 ± 2.00 11.6 ± 1.33 0.576
Hematocrit (%) 36.30 ± 3.61 33.5 ± 3.59 32.5 ± 6.33 36.7 ± 4.06 0.392
Mean red blood cell volume (fL) 54.5 ± 2.88 54.0 ± 3.37 55.0 ± 2.10 57.2 ± 3.49 0.368
Mean cell hemoglobin (pg) 17.8 ± 0.40 17.7 ± 0.44 18.2 ± 0.40 18.1 ± 0.61 0.368
Mean cell hemoglobin concentration (g/dL) 32.7 ± 1.35 32.9 ± 1.86 33.0 ± 1.03 31.6 ± 1.18 0.336
Red blood cell distribution width (%) 15.3 ± 0.92 15.1 ± 0.82 15.0 ± 0.35 15.6 ± 1.57 0.790
Platelets (109/L) 426 ± 62.7 570 ± 383.0 691 ± 127.8 513 ± 157.5 0.455
Plateletcrit (%) 0.26 ± 0.126 0.33 ± 0.181 0.63 ± 0.487 1.68 ± 2.282 0.210
Mean platelet volume (fL) 7.3 ± 0.26 6.1 ± 0.88 6.0 ± 0.98 6.4 ± 0.75 0.065
  1. Units are in brackets. The results are means of multiple determinations (n = 6) with ± standard deviation