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Table 4 Mean hematologic parameters of the whole blood of rats

From: Biodistribution of a High Dose of Diamond, Graphite, and Graphene Oxide Nanoparticles After Multiple Intraperitoneal Injections in Rats

Parameters

DN

GN

GO

Placebo

ANOVA

P value

White blood cells (109/L)

3.01 ± 1.748

3.08 ± 1.715

2.03 ± 1.179

3.13 ± 1.496

0.586

Lymphocytes (109/L)

2.65 ± 1.592

2.56 ± 1.473

1.75 ± 1.059

2.32 ± 0.665

0.622

Monocytes (109/L)

0.08 ± 0.059

0.10 ± 0.049

0.06 ± 0.043

0.09 ± 0.033

0.309

Granulocytes (109/L)

0.29 ± 0.207

0.43 ± 0.259

0.22 ± 0.104

0.73 ± 1.146

0.515

Red blood cells (1012/L)

6.67 ± 0.729

6.23 ± 0.674

5.88 ± 1.018

6.43 ± 0.813

0.440

Hemoglobin (g/dL)

11.8 ± 1.10

11.0 ± 1.29

10.7 ± 2.00

11.6 ± 1.33

0.576

Hematocrit (%)

36.30 ± 3.61

33.5 ± 3.59

32.5 ± 6.33

36.7 ± 4.06

0.392

Mean red blood cell volume (fL)

54.5 ± 2.88

54.0 ± 3.37

55.0 ± 2.10

57.2 ± 3.49

0.368

Mean cell hemoglobin (pg)

17.8 ± 0.40

17.7 ± 0.44

18.2 ± 0.40

18.1 ± 0.61

0.368

Mean cell hemoglobin concentration (g/dL)

32.7 ± 1.35

32.9 ± 1.86

33.0 ± 1.03

31.6 ± 1.18

0.336

Red blood cell distribution width (%)

15.3 ± 0.92

15.1 ± 0.82

15.0 ± 0.35

15.6 ± 1.57

0.790

Platelets (109/L)

426 ± 62.7

570 ± 383.0

691 ± 127.8

513 ± 157.5

0.455

Plateletcrit (%)

0.26 ± 0.126

0.33 ± 0.181

0.63 ± 0.487

1.68 ± 2.282

0.210

Mean platelet volume (fL)

7.3 ± 0.26

6.1 ± 0.88

6.0 ± 0.98

6.4 ± 0.75

0.065

  1. Units are in brackets. The results are means of multiple determinations (n = 6) with ± standard deviation

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