Table 1 The effectiveness of 5-FU, MI-1, and C₆₀FAS at DMH-induced colon cancer (M ± m; n = 15)

Average number of tumors, per rat

Cecum

2.8 ± 0.4

1.8 ± 0.3

1.2 ± 0.1*

1.3 ± 0.2*

Colon

11.5 ± 1.0

9.0 ± 0.4

8.3 ± 0.2*

8.6 ± 0.7*

Rectum

2.6 ± 0.3

2.8 ± 0.4

2.0 ± 0.3

1.9 ± 0.2

All parts

16.8 ± 1.0

13.5 ± 0.7

11.5 ± 0.3*

11.8 ± 0.8*

Average area of tumors, mm²

Cecum

9.6 ± 1.8

6.4 ± 1.0

9.4 ± 1.7

5.0 ± 1.0*

Colon

15.0 ± 1.6

9.0 ± 0.5

11.2 ± 0.7

11.6 ± 0.5

Rectum

22.0 ± 2.1

18.6 ± 2.1

18.4 ± 1.1

16.1 ± 2.0

All parts

14.5 ± 1.1

10.3 ± 0.5*

12.1 ± 0.6

11.4 ± 0.5*

Total area of tumors, per rat, mm²

Cecum

30.5 ± 8.1

11.1 ± 2.0

10.5 ± 1.6*

6.3 ± 1.2*

Colon

158.9 ± 11.7

79.7 ± 1.8*

95.0 ± 7.8*

100.9 ± 10.3*

Rectum

51.9 ± 5.1

45.8 ± 5.5

34.6 ± 3.3*

29.2 ± 4.7*

All parts

241.3 ± 16.4

136.6 ± 6.1*

140.0 ± 10.3*

136.4 ± 12.9*