Fig. 10
From: The Potential Liver, Brain, and Embryo Toxicity of Titanium Dioxide Nanoparticles on Mice
Changes in the ROS, antioxidant enzymes, NO signaling, glutamate, and AchE activities in brains of mice exposed to nano-TiO2. Mice were treated with nano-TiO2 suspension or saline solution as indicated through intraperitoneal injection once a day for 14 days. N = 10, * compared to control, P < 0.05; # compared to control, P < 0.01. a Change of ROS (O2-, H2O2, and MDA) in brains of mice exposed to nano-TiO2. b Change of antioxidant enzymes (SOD, CAT, APX, and GSHPx) in brains of mice exposed to nano-TiO2. c Change of NO signaling components (cNOS, iNOS, and NO) in brains of mice exposed to nano-TiO2. d Change of glutamate content and AchE activity in brains of mice exposed to nano-TiO2