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Table 3 The percentages of rat glioma C6 cells for each level of genotoxicity after 6 h of treatment with the free form of compounds Les-3288 and Les-3833, and their complexes with the polymeric nanocarrier (PNC)

From: Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

Sample	Comet class (% of cells)					DI
Sample	0	1	2	3	4	DI
Control	72.0 ± 0.5	28.0 ± 0.6				28.00 ± 0.58
Les-3288	25.3 ± 0.2	28.0 ± 0.6	37.3 ± 0.1	8.0 ± 0.3	1.3 ± 0.1	131.80 ± 0.74***
Les-3288 + PNC	62.6 ± 0.2	14.7 ± 0.9	10.7 ± 0.3	12.0 ± 0.6		72.10 ± 3.29***
Les-3833	12.0 ± 0.2	12.0 ± 0.6	41.4 ± 1.3	33.3 ± 0.2	1.3 ± 0.1	199.90 ± 2.35***
Les-3833 + PNC	10.6 ± 0.2	56.0 ± 0.3	16.0 ± 0.1	12.0 ± 0.1	5.3 ± 0.1	145.20 ± 0.85***
PNC	74.6 ± 0.9	25.3 ± 0.2				25.30 ± 0.17
Dox	12.0 ± 0.1	30.6 ± 0.4	25.3 ± 0.3	24.0 ± 0.2	8.0 ± 0.1	185.2 ± 0.23***

Damage index (DI): ***P < 0.001 compared with untreated control cells

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