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Fig. 7 | Nanoscale Research Letters

Fig. 7

From: Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis

Fig. 7

FMT reduces the immunosuppressive properties of MDSCs. a CD3+CD4+ cell populations in spleens were detected by FACS. b Quantitative data of a. c CD3+CD8+ cell populations in spleens were detected by FACS. d Quantitative data of a. e Ability of G-MDSCs from mice to suppress T cell proliferation induced by anti-CD3/CD28 stimulation was measured by FACS (n = 3 per group). A representative histogram is shown. f Ability of M-MDSCs from vehicle- or FMT-treated LPS-challenged mice to suppress T cell proliferation induced by anti-CD3/CD28 stimulation was measured by FACS (n = 3 per group). A representative histogram is shown. g, h Arg-1 and p47phox mRNA expression in MDSCs from vehicle or FMT-treated LPS-challenged mice

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