RETRACTED ARTICLE: Long Non-coding RNA MALAT1/microRNA-143/VEGFA Signal Axis Modulates Vascular Endothelial Injury-Induced Intracranial Aneurysm

Table 2 Relationship between relative expression of MALAT1 and clinicopathological features in patients with intracranial aneurysm

Clinicopathologic data	n	Expression of MALAT1		P
Clinicopathologic data	n	Low expression group (n = 12)	High expression group (n = 8)	P
Age (year)
≤ 42	8	5	3	0.852
> 42	12	7	5	0.852
Gender
Male	11	7	4	0.714
Female	9	5	4	0.714
Hunt-Hess grade
I/II	14	6	8	0.002
IIII/V	6	6	0	0.002
Degree of endothelial damage
0~2	6	1	5	0.010
3~4	14	11	3	0.010
Surgical mode
Clippping surgery	11	7	4	0.446
Conservative treatment	7	3	4
Interventional treatment	2	2	0
Smoking history
Smoking	15	11	4	0.035
Non-smoking	5	1	4	0.035

Note: MALAT1 metastasis-associated lung adenocarcinoma transcript 1; Grade 0: endothelial cells were basically normal, a few granulocytes attached to the gap; Grade 1: the gap between endothelial cells widened and intercellular filaments changed, but there was no obvious interruption of endothelial continuity; Grade 2: local endothelial cell damage and blood cell adhesion, other areas were covered by normal endothelial cells; Grade 3: the destruction of endothelial cell layer and the attachment of blood cells were large, and normal endothelial cells were still covered in the distant area; Grade 4: destruction of extensive endothelial cell layer, obvious attachment of blood cells, and the presence of a few endothelial cells. The data in this table are enumeration data, which are tested by chi-square test