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Fig. 2 | Nanoscale Research Letters

Fig. 2

From: Development and Evaluation of a System for the Semi-Quantitative Determination of the Physical Properties of Skin After Exposure to Silver Nanoparticles

Fig. 2

NaOH pretreatment is the optimal method for detecting nAg100 in dermis and epidermis. Two solubilizing reagents (HNO3 and NaOH) were screened as pretreatment solvents to lyse tissues. The epidermis (E) and dermis (D) homogenates were mixed with nAg100 to obtain a final Ag concentration of 100 ng/mL and treated with each solubilizing reagent at 37 °C. After 3 h, all samples were analyzed via ICP-MS and sp-ICP-MS. The a recovery rate of Ag, b nAg (black bars) and Ag+ (shaded bars) recovery rate, and c average particle diameters are presented. The dashed line represents the initial particle size. The data have been expressed as mean ± S.D. (n = 3)

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