Fig. 4

Restored miR-499-5p or depleted Sox6 reduces TNF-α, IL-1β and IL-6 contents in BALF and lung tissues of sepsis-induced lung injury mice. a TNF-α content in BALF of mice in each group. b IL-1β content in BALF of mice in each group. c IL-6 content in BALF of mice in each group. d protein bands of TNF-α, IL-1β and IL-6 in lung tissues of mice in each group. e protein expression of TNF-α in lung tissues of mice in each group. f protein expression of IL-1β in lung tissues of mice in each group. G protein expression of IL-6 in lung tissues of mice in each group. (a) P < 0.05 versus the sham group. (b) P < 0.05 versus the agomir NC group. (c) P < 0.05 versus the si-NC group. (d) P < 0.05 versus the miR-499-5p agomir + oe-NC group. Measurement data were depicted as mean ± standard deviation, and data were assessed by one-way ANOVA followed by Tukey’s post hoc test