Table 1 Application of drug delivery technology based on different cells in cancer
Cell | Encapsulated NPs | Drugs | Types of tumors | References |
|---|---|---|---|---|
Erythrocyte | ||||
PLGA NPs | Curcumin | Liver cancer | Xie et al. [7] | |
MnFe2O4 NPs | IR-780 | Sousa Junior et al. [8] | ||
Fusing tumor cell membrane-associated antigens with nanoerythrosomes | aPD-L1 | Breast cancer, melanoma | Han et al. [9] | |
PB NPs | Gamabufotalin | Breast cancer | Liu et al. [10] | |
siRNA, DOX | Breast cancer | Wang et al. [11] | ||
PB/manganese dioxide NPs | DOX | Breast cancer | Peng et al. [12] | |
PLGA NPs | DOX | AML | Aryal et al. [13] | |
Mesoporous silica NPs | Ce6, DOX | Breast cancer | Su et al. [14] | |
Metal–organic framework NPs | Glucose oxidase Tirapazamine | Colon cancer | Zhang et al. [15] | |
PLGA NPs | DOX | Lymphoma | Luk et al. [16] | |
Platelet | ||||
Chitosan oligosaccharide–PLGA copolymer | Bufalin | Liver cancer | Wang et al. [17] | |
Liposome | DOX | Breast cancer | Liu et al. [18] | |
PLGA NPs | ICG, aPDL1 | Breast cancer | Han et al. [19] | |
DOX | Lymphoma | Xu et al. [20] | ||
Epirubicin | Myeloma | Dai et al. [21] | ||
Immunological cell | ||||
Macrophage | ||||
DOX | Lung cancer | Evangelopoulos et al. [22] | ||
Gold nanorods | Liposome DOX | Breast cancer | Nguyen et al. [23] | |
Au nanoshells | DTX | Breast cancer | Choi et al. [24] | |
PLGA NPs, Fe3O4 magnetic NPs | Colon cancer, breast cancer | Han et al. [25] | ||
Cytotoxic T cells | ||||
PLGA NPs | Taxol | Gastric cancer | Zhang et al. [26] | |
Leukocyte | ||||
DOX | Breast cancer melanoma | Molinaro et al. [27] | ||
NK cell | Deng et al. [28] | |||
TCPP | Breast cancer | |||
Tumor cell | ||||
PLGA NPs | ICG | Breast cancer | Chen et al. [29] | |
Upconversion NPs | Breast cancer | Rao et al. [30] | ||
PLGA NPs | Cancer cell membrane fractions | Glioblastoma | Jin et al. [31] | |
Magnetic iron oxide NPs | DOX | UM-SCC-7 | Zhu et al. [32] | |
Stem cell | ||||
AlPcS4@FNPs | Osteosarcoma | Lenna et al. [33] | ||
Ce6 | Lung melanoma | Ouyang et al. [34] | ||
Polydopamine NPs Gelatin nanogels | DOX | Cervical carcinoma | Gao et al. [35] |