Fig. 3

Reduced miR-216b is tested in EC; Overexpressing miR-216b suppresses EC cell progression. a miR-216b expression was low in EC tissues versus normal tissues (n = 68) in RT-qPCR; b miR-216b expression was decreased in EC cell lines versus NE cells (RT-qPCR); c miR-216b expression was elevated by miR-216b mimic in lshikawa cells (RT-qPCR); d Cell viability was suppressed by miR-216b mimic (MTT assay); e Cell apoptosis rate was induced by miR-216b mimic (flow cytometry); f Cell migration was limited by miR-216b mimic (scratch test); g Cell invasion was weakened by miR-216b mimic (Transwell assay). The data were expressed as mean ± standard deviation (N = 3). ^#P < 0.05 versus the mimic NC group