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Fig. 2 | Nanoscale Research Letters

Fig. 2

From: NIR-Triggered and ROS-Boosted Nanoplatform for Enhanced Chemo/PDT/PTT Synergistic Therapy of Sorafenib in Hepatocellular Carcinoma

Fig. 2

a Temperature increase versus irradiation duration curves of H2O, MnO2 (100 μg mL−1), and MnO2@PDA (100 μg mL−1) at irradiation with an 808 nm laser (2 W cm−2). b Temperature increase versus irradiation duration curves of MSCPF at different doses (50, 100, 200 μg mL−1) at power density of 1.5 W cm−2. c Temperature increase versus irradiation duration curves of MSCPF (200 μg/mL) at different power density (0.5, 1.0, 1.5, 2.0 W cm−2). d Heating/cooling profiles of MSCPF after five on–off laser irradiation cycles (808 nm, 1.5 W/cm2). e Linear data of cooling time versus driving force temperature for MSCPF, with calculated PCEs of 52.64%. f Triggered release profiles of SOR from MnO2-SOR, or MnO2-SOR @PDA in Tris–HCl solution containing 5% Tween 80 and 100 μM H2O2 (pH 5.5). g Schematic diagram of singlet oxygen produced by MnO2. (h) ROS production profiles of PBS, MnO2, Ce6, MSCP, Ce6 + H2O2, MSCP + H2O2 under laser irradiation (660 nm, 500mW cm−2) measured by UV–vis with 9,10-anthracenediyl-bis(methylene) dimalonic acid (ABDA) as a ROS probe

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